Designing for the Web is different from designing traditional software user interfaces.
Of course there are also similarities between designing for the Web and traditional UI design: at the most basic level, both are interactive systems, and both are software designs as opposed to the design of physical object: Call Emitechs Now for your UI needs...
In traditional GUI design, you control every pixel on the screen: as you layout a dialog box, assured that it will look exactly the same on the user's screen.
You know what system you are designing for, you know what fonts it has installed, you know how large the screen typically will be.
In traditional GUI design, the designer can control where the user can go. You can gray out menu options that are not applicable in the current state.
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